comfrey cream holland and barrett

J Hepatol 2003;39:437-46. It is easily absorbed to leave your skin feeling fresh, soft and radiant. Comfrey has been claimed to heal gastric ulcers and hemorrhoids, and to suppress bronchial congestion and inflammation. Grube, B., Grunwald, J., Krug, L., and Staiger, C. Efficacy of a comfrey root (Symphyti offic. Regul Toxicol Pharmacol. Comfrey has been used medicinally for at least 2000 years for various conditions, including bone fractures, ulcers, and gout. Can comfrey be used for cracked nipples during breastfeeding? This article discusses the uses and benefits of comfrey cream. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: Results of a randomized controlled clinical double-blind study. View abstract. Recent studies have suggested topical benefits, but more research is needed. (2013). Ministry of Environment & Forests, Govt. In Western Europe, comfrey has been used topically for treating inflammatory disorders such as arthritis, gout, and thrombophlebitis, and internally for treating diarrhea. Brassica Campest is Seed Oil (Rapeseed Oil), Symphytum Officinale Herb (Comfrey Herb), BHA, Eucalyptus Globulus Leaf Oil (Eucalyptus Oil). Shop buy 1 get 1 half price on all gut health products, Buy 1 get 1 Half Price | Plus an extra 20% off 25, App Exclusive | Get an extra 22% off 25 when you spend on the H&B App, Royal Mail strikes may cause a delay to our click and collect service, Looking for fitness advice & inspiration this New Year? Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., and Staiger, C. Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study. New South Wales Health, Australia. Using a combination product makes it challenging to know how much of the beneficial effect came from comfrey alone. The Food and Drug Administration (FDA) released an advisory in July 2001 recommending that comfrey products be removed from the market because of cases of hepatic veno-occlusive disease. Z Phytotherapie 2000;21:127-134. *PR sample. 2012;101(4):211-216. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Kucera, M., Kalal, J., and Polesna, Z. It should never be taken by mouth. Facebook; Twitter; Pinterest; Related Posts. MedlinePlus Medical Encyclopedia. The Pharmaceutical Journal, PJ, December 2007. 2008;54(1):7-20. Complement Ther Clin Pract. Toe was infected and painful. 1 Since at least the 4 th century, people have used comfrey medicinally. This comfrey cream recipe works great for local areas that have mild bruising or soft tissue pain. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments. Navarro VJ, Khan I, Bjrnsson E, Seeff LB, Serrano J, Hoofnagle JH. Do not use more of this product than is recommended on the label. Comfrey root extracts have been used by herbalists and in folk traditions for centuries to soothe aches and pains. Latest: Senior Software Engineer - Front End Senior Software Engineer Senior Product Manager - Basket, Checkout and Payments UX Designer - Instore Tech. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Vickers AJ, Vertosick EA, Lewith G, et al. After the tincture is made, then you can whip up the fabulous joint and muscle cream! Do not use comfrey with very young children or during pregnancy or lactation. Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). She is passionate about providing evidence-based recommendations that make health decisions easier and improve lives. Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). Staiger, C. Comfrey: a clinical overview. Choose organically grown comfrey when possible. Comfrey contains chemicals that can cause liver damage, lung problems, or cancer. Without overexposure to air or heatand without cross-contaminationthe recipe should last as long as the expiration date of the carrier oils used. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Supplements marketed for body-building (ex.. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Store at room temperature away from moisture and heat. Copyright Holland & Barrett Retail Limited, 2022. Osteoarthritis Cartilage. Choose organically grown comfrey when possible. J Chiropr Med. These include allantoin, rosmarinic acid, and others. This was compared to 37.8% in the placebo group. Remove from heat. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. Click to share on Facebook (Opens in new window), Click to share on Pinterest (Opens in new window), Click to share on Twitter (Opens in new window), Click to share on LinkedIn (Opens in new window), Click to share on Tumblr (Opens in new window), Click to share on Reddit (Opens in new window), Click to email a link to a friend (Opens in new window), Try A Cooling Herbal Compress for Hot Summer Days, Handmade Floral Paper: A Family-Friendly Project, Making Herbal Preparations 101 Mini Course, Emulsifiers and Preservatives in Botanical Skin Care Products. Using different formulations together increases the risk of an overdose. July 6, 2001. As we are constantly reviewing and developing our products to meet our consumer needs, consumers, particularly those that suffer from allergies and intolerances, should always check product labelling, warnings, and directions provided with the product that is delivered, prior to use or consumption. This makes quite a thick rich cream good for a body cream and an all healing cream . Medicine makers would bind comfrey leaves and roots in poultices, then apply those poultices to the skin to treat injuries. Need some help with an order or want to speak to a member of our Customer Services team? You may report side effects to FDA at 1-800-FDA-1088. . hollandandbarrett.ie is a trading name of Holland & Barrett Retail Limited. Make sure to always buy comfrey. how to become a school board member in florida ocean deck band schedule When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: results of a double-blind, randomised, bicenter, placebo-controlled trial. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. This site uses cookies to improve your experience. Phytomedicine, 11(6), 470-477. https://doi.org/10.1016/j.phymed.2004.02.001, Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. Call your doctor for medical advice about . Rad. Comfrey also is known as Russian comfrey, knitbone, radix consolidate, bruisewort, blackwort, and slippery root. Stam, C., Bonnet, M. S., & van Haselen, R. A. To Use. WebMD does not provide medical advice, diagnosis or treatment. View abstract. View abstract. Some people ingest comfrey roots or leaves or use them in teas. Registered VAT no. This perennial can grow up to 4-feet tall. Consult your healthcare provider before using. View abstract. , 43 volunteers with osteoarthritis used either a topical cream containing comfrey, tannic acid, and eucalyptus or a placebo cream 3x/ day for 6 weeks. Comfrey may have been applied to the skin in a specific preparation to treat some of these conditions. Set on a sunny windowsill and shake once a day for 2-4 weeks. Join Rewards for Life today and we'll give you 300 points worth 3, Save 5% on your favourite products, plus get the lowest price from the last 90 days and free delivery on orders over 10. Comfrey root: from tradition to modern clinical trials, Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo-controlled, multicentre trial, Topical herbal therapies for treating osteoarthritis, Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials, Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Arzneimittelforschung. of India has issued Environment Impact Assessment EIA Notification dated 14th September, 2006 for according Environment Clearance(EC) to 8 categories of industries/projects by the Ministry of Environment & Forests, Govt. Arzneimittelforschung. Please simply create an account before buying/booking any courses. (3), 147-156. https://doi.org/10.1016/j.jcm.2011.01.003. Company number 02758955 Registered VAT number 211727395. The plant has a long history in folk and ancient herbal treatments before comfrey is . Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., Giannetti, B., Klingenburg, S., and Staiger, C. Efficacy and tolerance of a comfrey root extract (Extr. Aust.J Physiother. Avoid taking comfrey orally (by mouth). Results of an observational study of patients]. Learn more in. Here's 10 things essential oils are great for. The use of babosa (Aloe vera) in treating burns: a literature review. Please read the Topical Use Safety section of this article (above) before using. British journal of sports medicine, 44(9), 637-641. https://doi.org/10.1136/bjsm.2009.058677, Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). 98% Naturally derived. Dietary supplements are not regulated like drugs in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. Dietary Supplements: What You Need to Know. Barna, M., Kucera, A., Hladicova, M., and Kucera, M. [Wound healing effects of a Symphytum herb extract cream (Symphytum x uplandicum NYMAN: ): results of a randomized, controlled double-blind study]. Other drugs may interact with comfrey, including prescription and over-the-counter medicines, vitamins, and herbal products. Many of those following the folk use of comfrey up to present-day think so. Registered VAT no. Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., & Staiger, C. (2004). Do not give any herbal/health supplement to a child without medical advice. Taking comfrey along with a medication that can harm the liver might increase the risk of liver damage. Pyrrolizidine alkaloids are very toxic to the liver and are also carcinogenic (cause cancer). Looks like you may need to upgrade your browser We're sorry, we no longer support the web browser that you are using Topically applied comfrey oil is associated with a wide range of health benefits and can help with certainissues including: Comfrey oil is good at helping with superficial cuts, scratches, and scrapes. After eight days, the group that used the cream had significantly less pain than those who had the placebo. Commercial comfrey sale and distribution is restricted in Germany and Canada because of its substantial toxicity. Also, avoid use for more than two weeks or excessive concentrations containing more than 100 mcg of pyrrolizidine alkaloids (Wichtl, 2004 & Ulbricht, 2010). A review of 26 clinical trials concluded that mild skin reactions were the most common side effects of comfrey creams used in the studies. Herbal medicine for low back pain: A Cochrane review, Dietary Supplements: What You Need to Know, Sinusoidal obstruction syndrome (blockage of veins in the liver). Dosage: How Much Comfrey Cream Should I Use? Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. In 2001, the Food and Drug Administration (FDA) banned oral comfrey products. It can grow up to 5 feet tall. Ask your doctor if you have any questions. 1 It's found in Europe, Asia, and North America. It should only be used in small amounts for short periods as a cream. 6 Healing Benefits of Comfrey. doi:10.1002/14651858.CD010538, Smith DB, Jacobson BH. root extraction help ease aching joints and muscles? Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. of India and by a State Level Environment Impact Assessment Authority constituted by Government of India on the recommendations made . DOI:10.1211/PJ.2021.1.69803. Kuera, M., Barna, M., Horek, O., Kovrikov, J., & Kuera, A. Fitoterapia. Using it no more than four to six weeks a year as a general guideline would be best. Mei N, Guo L, Fu PP, Fuscoe JC, Luan Y, Chen T. Metabolism, genotoxicity, and carcinogenicity of comfrey. 2012;(1):41-42. Topical comfrey is for use only on the skin. Researchers have found it does seem to reduce pain in some conditions, including back pain, osteoarthritis, and ankle sprains. Kucera, M., Barna, M., Horacek, O., Kovarikova, J., and Kucera, A. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: results of a randomized controlled clinical double blind study. Would you like to win our brilliant Botanical Business Package with nearly $1,000 in prizes? Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Quis autem velum iure reprehe nderit. Mackinnon, M. In general practice, 'always expect the unexpected'. Find out how to use it here along with its benefits. Join Rewards for Life today and we'll give you 300 points worth 3, Save 5% on your favourite products, plus get the lowest price from the last 90 days and free delivery on orders over 10. We are building the future of Health and Wellness Tech. Efficacy and tolerance of a comfrey root extract (Extr. Comfrey Uses, Benefits & Side Effects - Drugs.com Herbal Database (21), 498-507. https://link.springer.com/article/10.1007/s10354-004-0114-8, Natural Medicines (2020). View abstract. Pyrrolizidine poisoning. Avoid using comfrey together with other herbal/health supplements that can also harm the liver. The efficacy and safety of comfrey. comfrey cream holland and barrett - daxasys.com We cover all you need to know in this article. Some drugs increase how quickly the liver changes and breaks down comfrey. Bergamot oil is one of the most popular essential oils, but what is it & what are the benefits of using it? D'Anchise, R., Bulitta, M., and Giannetti, B. Comfrey extract ointment in comparison to diclofenac gel in the treatment of acute unilateral ankle sprains (distortions). Adv.Ther 2000;17(4):204-210. Palestrica of the Third Millennium Civilization & Sport. Herb & Supplement Guide. 2012;26(10):14411448. In another study, participants with ankle sprains received either comfrey root extract cream or diclofenac gel, a nonsteroidal anti-inflammatory drug (NSAID). Close LOGIN FOR DONATION. Available for Android and iOS devices. Comfrey is generally considered unsafe, with numerous toxicological effects in animals and humans. Do not use this product without medical advice if you are pregnant. OTHER NAME(S): Ass Ear, Black Root, Blackwort, Bruisewort, Common. Skip the missed dose if it is almost time for your next scheduled dose. Comfrey oil shouldnt be used for cooking, like other types of cooking oil. View abstract. Newer Post Older . View abstract. Barna, M., Kucera, A., Hladikova, M., & Kucera, M. (2012). 2021;83:e249209. J Toxicol Environ Health B Crit Rev. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. In some cases, ointments with comfrey have caused redness, itching, and a rash (Smith, 2011). View abstract. Stickel F, Seitz HK. The FDA has recommended that all comfrey products that are taken by mouth be removed from the market. We go to great efforts to ensure that the information on this page is accurate at the time that the page was last edited. 2007;157(21-22):569-574. We comply with the HONcode standard for trustworthy health information. cup organic safflower oil Comfrey oil is a herbal oil that moisturises skin, and that's been used as a healing herb for a long time. Complementary Health Approaches for Chronic Pain: What the Science Says. Food and Drug Administration. Jurcu, R., & Jurcu, I. 2018;19(5):455-474. doi:10.1016/j.jpain.2017.11.005, Gagnier JJ, Oltean H, van Tulder MW, Berman BM, Bombardier C, Robbins CB. First, make the comfrey root tincture by combining the dried comfrey root and alcohol in a sterilized, dry, glass pint jar. This is not a complete list of side effects and others may occur. This recipe is contraindicated for small children and those with certain medical conditions. Registered office: Samuel Ryder House, Barling Way, Nuneaton, Warwickshire CV10 7RH. Public Health Nutr 2000;3:501-8. Like any new treatment, discontinue use if any irritation occurs. We're proud to make a difference, and you can to. Shop buy 1 get 1 half price on all gut health products, Buy 1 get 1 Half Price | Plus an extra 20% off 25, App Exclusive | Get an extra 22% off 25 when you spend on the H&B App, Royal Mail strikes may cause a delay to our click and collect service, Looking for fitness advice & inspiration this New Year? 1.35 Fl Oz. Stop using comfrey and call your healthcare provider at once if you have: liver problems-- nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Copyright Holland & Barrett Retail Limited, 2022. After the tincture is made, then you can whip up the fabulous joint and muscle cream! Terry Naturally Traumaplant Comfrey Cream - amazon.com In a randomized, controlled, double-blind study with 203 patients, applications of a 10% comfrey cream were well tolerated, reduced swelling and pain, and improved mobility (Kucera et al., 2004). 7-6-2001; Lin, C. C., Yang, C. C., Phua, D. H., Deng, J. F., and Lu, L. H. An outbreak of foxglove leaf poisoning. Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage are appropriate for your individual needs. The study involved 43 patients with knee osteoarthritis and a six-week treatment period. Knee pain and stiffness can be a stubborn concern that keeps many from doing activities they enjoy. View abstract. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Buy 1 get 1 Half Price | Plus an extra 20% off 30, Shop buy 1 get 1 half price on all gut health products, Looking for fitness advice & inspiration this New Year? Comfrey is an herb in the Boraginaceae family and has small purple flowers. Do not use extra comfrey to make up the missed dose. All rights reserved. Begin mixing on low. reduce lower back pain (Stam et al., 2001). Comfrey. https://doi.org/10.1007/s10354-007-0474-y. If you choose to use comfrey, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Toxicol Lett 2005;155:411-20. Comfrey [Online article]. Thus, it is not advised to ingest herbal preparations of comfrey unless guided by an expert pharmacologist and physician. Study results revealed that pain intensity during active movement decreased an average of 95.2% in the group given comfrey ointment. Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). Comfrey has been cultivated as a green vegetable and has been used as an herbal medicine for more than 2,000 years. Pharmazie 1995;50:83-98. COMFREY: Overview, Uses, Side Effects, Precautions - WebMD Kucera, M., Barna, M., Horacek, O., Kalal, J., Kucera, A., and Hladikova, M. Topical symphytum herb concentrate cream against myalgia: a randomized controlled double-blind clinical study. comfrey cream holland and barrettfeathered friend questions and answers. Glass bowl with a lid However, further well-designed studies are needed. However, not a rate considered harmful for those with healthy livers.10,11, Masters Degree in Toxicology and BSc Hons in Medical Biochemistry. The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). Preclinical studies suggest that oral comfrey has antiproliferative effects , and a topical formulation showed wound healing properties . Nat Prod Res 2018;32(5):605-9. doi: 10.1080/14786419.2017.1326492. Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). 2013;21(6):724-745. doi:10.1016/j.ctim.2013.09.009. Comfrey can also contain echimidine, pyrrolizidine alkaloids (PAs), and symphytine, which can damage the liver, are carcinogenic (cancer-causing) and may harm a fetus. Transfer the cooled oil and butter mixture to a standing electric mixer or blender. The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). View abstract. Copyright Holland & Barrett Limited 2023. Soaked foot in warm water with a few leaves of comfry. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Three clinical studies have provided evidence that ointments containing comfrey root have helped reduce back pain. This is the tincture. Our associates are qualified to advise, visit us online or in store for unparalleled advice. Apply a small amount (not to exceed a teaspoon) topically 2-3x/day for up to 2 weeks. Regarding its antioxidant, antilipoperoxidant, antiinflammatory, and cytotoxic properties. Comfrey Definition & Meaning - Merriam-Webster View abstract. View abstract. Lorem ipsum dolor sit nulla or narjusto laoreet onse ctetur adipisci. J Chiropr Med. The cream was applied to the local lumbar area 4x during the day of the exercise, with the first application being pre-exercise (Jurcau & Jurcau, 2013). Symphyti) in the treatment of ankle distorsions: Results of a multicenter, randomized, placebo-controlled, double-blind study. 12 drops juniper berry (Juniperus communis) essential oil 2019;24(12):2272. doi:10.3390/molecules24122272, Staiger, Christine. Nutrition C for FS and A. The use of babosa (Aloe vera) in treating burns: a literature review. Potters Comfrey Ointment | Holland & Barrett Beth Thomas, PharmD, is a clinical pharmacist and founder of BMT Consulting Services, LLC. Penetration of lycopsamine from a comfrey ointment through human epidermis. Amendments to the poison list. 20 Rewards for Life points with this purchase, Potters Herbals Comfrey Ointment is a traditional herbal medicinal product used for the symptomatic relief of minor sprains and bruises, based on traditional use only. Comfrey can kill. Comfrey may also be used for purposes not listed in this product guide. This includes androstenedione, bishop's weed, borage, chaparral, comfrey, DHEA, echinacea, garlic, germander, golden ragwort, hound's tongue, kava, licorice, niacin (vitamin B3), pennyroyal oil, red yeast, St. John's wort, and others. For External Use only Do not use if you are sensitive to any of the ingredients. Copyright 1996-2023 Cerner Multum, Inc. Centurian, South Africa: Medpharm Scientific Publishers. Comfrey is often sold as an herbal supplement. Select a condition to view a list of vitamins. Comfrey flowers are bell-shaped and purple, pink, or pale yellow in color, and it has a dark taproot. To make this recipe, first, you must prepare the comfrey root tincture. Comfrey - The Lost Herbs And topical capsaicin cream may help to relieve pain temporarily. Efficacy of a comfrey root extract ointment in comparison to a Diclo-fenac gel in the treatment of ankle distortions: Results of an observer-blind, randomized, multicenter study. Spine(Phila Pa 1976). Add comfy to Vaseline . A critical scoping review of external uses of comfrey (Symphytum spp.). Thus, it is not advised to ingest herbal preparations of comfrey unless guided by an expert pharmacologist and physician. These have a lower risk of serious side effects like liver damage. Liver injury from herbal and dietary supplements. This perennial can grow up to 4-feet tall. Do not take comfrey without medical advice if you are using any of the following medications: This list is not complete. Published 2021 Sep 20. doi:10.1590/1519-6984.249209, Frost R, MacPherson H, O'Meara S. A critical scoping review of external uses of comfrey (Symphytum spp.). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. We cover all you need to know in this article. When considering the use of herbal supplements, seek the advice of your doctor. Comfrey Oil: Benefits, Uses & Risks | Holland & Barrett The efficacy and safety of a homeopathic gel in the treatment of acute low back pain: a multi-centre, randomised, double-blind comparative clinical trial. Phytomedicine, 14(1), 2-10. https://doi.org/10.1016/j.phymed.2006.11.006, Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). The following applications have been used in research: Using large amounts of comfrey cream or using it for extended periods of time increases the risk of side effects like liver toxicity. The warm weather has a way of encouraging us to get outside and move our bodies more. 2 Comfrey cream contains several active components (substances). FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. What is niacinamide? Comfrey (Symphytum officinale) is a plant with yellow or purple flowers found in Europe, Asia, and North America. Holland Barrett | Careers Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. However, people with knee pain may be glad to try a topical preparation that could help in addition to any other recommendations made by their physician. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Lewis, C. J. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. This information may not fit your specific health circumstances. Seal with a lid and then label with the ingredients and date. While larger and more studies are needed to fully determine safety and effectiveness, short term topical application of comfrey may give you peace of mind, relief, and support while you rest and heal, following any additional advice from your physician. It also came as a reference to the belief that comfrey can mend broken bones. 2011;10(3):147-56. doi:10.1016/j.jcm.2011.01.003, Laslett LL, Quinn SJ, Darian-Smith E, et al. Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Learn more in The Comfrey Controversy: Can and Should One Use Comfrey Internally? State Level Environment Impact Assessment Authority, Jharkhand cbd cream holland and barrett for pain relief Giannetti, B. M., Staiger, C., Bulitta, M., and Predel, H. G. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo controlled, multicentre trial.

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